April 09-10, 2021
Webinar
PULSUS is proud to host upcoming "2nd International Conference on Enzymology and Cell Biology " during April 09-10, 2021. This is a phenomenal open door for the members from Universities and Institutes to connect with the world class Scientists.
The wide subject inclusion of the Conference and its size give a great setting to members to increase important knowledge into progress in inquire about regions past their own. What's more a scope of exceptional sessions expects to connect with members on more extensive issues, for example, instructing in the enzymology and atomic science examine.
The Enzymology Conference has a solid accentuation on help and motivation for the up and coming age of researchers, alongside early-profession scientists, a Young Researchers Forum, and exercises to empower connection with companions and specialists.
By and large this meeting expects to be an unprecedented cross order assembling in the enzymology life sciences for look into introductions, dialogs, learnings, motivations and support with members leaving with new research information and thoughts, and maybe the beginnings of universal coordinated efforts and affiliations.
Target Audience :
Opportunities for participants:
Why to attend?
This Global conference provides the opportunity for many Professors, doctors, scientists, nurses and researchers from all worldwide to gather and learn the latest advances in the field of Biology and biotechnology and health maintenance and to discuss on scientific ideas and experiences in a special environment.
2 days of scientific exchange
150+ abstracts submitted
30+ scientific sessions
70+ international expert faculty members
80+ healthcare professionals
SESSION 1: ENZYME DISCOVERY
Both macromolecular and micro-molecular proteins are enzymes and are specifically located. They are biological macromolecular catalysts and they improve chemical reactions. Enzymology deals with, in addition to their relation to each other, the study of enzymes, their kinetics, structure, and function. In the universe, enzymes play an entirely essential role. If that reaction involves the execution of DNA for the cause of cellular repair or the digestion of some sort of meat or fowl, it acts as a catalyst for a chemical reaction. Biochemistry is the technology department that provides chemical strategies within and associated with resident species. Biochemistry focuses primarily on techniques that exist at the molecular level, such as within our cells, reading components such as proteins, lipids and organelles. It also looks at the manner in which cells communicate to each other. Biochemists need to understand how their function relates to the molecular structure and then enable them to expect the interaction of the molecules. Several medical fields are covered by biochemistry, including genetics, microbiology, forensics, plant technology and medicine.
SESSION 2: MOLECULAR ENZYMOLOGY
Molecular enzymology is the department of biochemistry that, in addition to the structural characteristics of the enzymes within a molecular degree, encircles or provides functionality. Enzymes are globular proteins that play an entirely vital role in every form of biochemical reaction as a catalyst. Molecular enzymology is focused on the design and synthesis of enzymes, and creative drug targets are based on unnecessary unmet medical desires. These works are focused solely on revolutionary targets for drugs. The hobby of molecular enzymology consists of all enzyme-related variables, such as enzyme discovery, enzyme structure, enzyme mechanisms, enzyme cell and metabolic capabilities, drug discovery, enzyme biochemical aspects, bioinformatics, computer analysis, molecular modelling science, newer enzyme expression strategies in addition to purification, bio catalysis.
SESSION 3: COMPUTATIONAL ENZYMOLOGY
The scientific subdiscipline that applies computational molecular simulation and enzyme modeling, in particular to the simulation of enzyme-catalyzed reactions, is computer enzymology. Computational enzymology is a rapidly growing and maturing scientific field that is gradually contributing to the understanding and practical application of enzyme catalysis mechanisms. The unique ability of computational modeling and simulation is to provide comprehensive, atomic-resolution insight into the dynamics and reactions of biomolecules. Calculations of the structure of Quantum Mechanical Electronics may be useful for modeling reactions in models of enzyme active sites. With hybrid quantum mechanics/molecular mechanics or empirical valence bond approaches, broader models can be handled with which simulations of molecular dynamics can be carried out. Molecular simulations of enzymes
Molecular modelling of enzymes
Fundamental mechanism of biological catalysts.
SESSION 4: ENZYME IMMOBILIZATION AND THERAPEUTICS
The highly selective biocatalysts that are synthesized by living cells are enzymes. Therapeutic enzymes are those enzymes that can be safely used medically, either isolated or in combination with other therapies for the treatment of different diseases. The basis for "The therapeutic use of enzymes" is the use of these enzymes as medications for the treatment of medical problems. For patients suffering from conditions affecting digestive processes such as Cysic fibrosis, Gaucher's disease and celiac disease, enzyme supplements are also recommended. Enzymes are capable of purifying the blood, enhancing the immune system, improving mental capability, cleaning the colon, and preserving the right balance of pH in the urine. Another wide area which is applied in therapeutics is enzyme immobilization. The method of immobilization is to improve an enzyme's operational efficiency for industrial usage. Immobilization enhances many enzyme properties, such as organic solvent efficiency, pH tolerance, selectivity, heat stability and functional stability..
Enzyme therapy in cancer
Therapeutic enzymes in drug delivery
Clinical application of immobilized enzymes
Whole cell immobilization
Immobilized enzymes in antibiotic production
Metallozymes
SESSION 5: ENZYMOLOGY AND THERMODYNAMICS
The reaction runs in the same direction as it does without the enzyme in the presence of an enzyme, just quicker. For instance, depending on the concentration of its reactants, carbonic anhydrase catalyses its reaction in either direction. The rate of a reaction depends on the energy of activation necessary to form the state of transition that then decays into products. By lowering the energy of the transition state, enzymes increase reaction rates. First, binding forms a low energy enzyme-substrate complex (ES). Secondly the enzyme stabilises the transition state such that it requires less energy to achieve compared to the uncatalyzed reaction (ES‡). Finally, the enzyme-product complex (EP) dissociates to release the products.
Catalytic mechanisms of enzymes
Enzyme-substrate complex
Transition state of enzymes
Transformation of substrate
Production of intracellular components
Production of extracellular metabolites
Production of biomass
Product recovery
Enzymes in food digestion
Applications of immobilized enzymes in food
Single cell protein
SESSION 6: ENZYMOLOGY CASE STUDY
A case study is typically a recorded study of a particular real-life circumstance or imagined scenario, used in business schools and firms as a teaching method. Students or trainees are required, assisted by the line of reasoning employed and conclusions made, to examine the prescribed cases and present their interpretations or solutions. The case study is made up of different notes that reflect the patient. The patient's data, such as test reports, medical history, family history, social history, physical exam, treatment plan, etc.
SESSION 7: GENETICS AND GENOMICS
Genetics is a term that refers to the study of genes and their inheritance functions - in other words, the transfer of certain characteristics or disorders from one generation to another. Genetics includes studies of genes and their results in scientific terms. Genes (heredity units) hold protein-making instructions that guide the activities of cells and body functions. Cystic fibrosis (See: Learning About Cystic Fibrosis), Huntington's disease (Learning About Huntington's Disease), and phenylketonuria (PKU) are examples of hereditary or inherited diseases (Learning About Phenylketonuria).
Genomics is a more modern concept describing the analysis of all genes (the genome) of an individual, including interactions of those genes with each other and with the environment of the person. The scientific study of complex diseases such as heart disease, asthma, diabetes, and cancer requires genomics, since these diseases are commonly triggered by a combination of genetic and environmental factors rather than individual genes. As well as modern testing tools, Genomics provides new possibilities for therapies and treatments for certain complex diseases.
Cellular and Molecular Genetics
Genomics: Disease and Evolution
Stem cells and Regenerative Medicine
Bioinformatics in Human Genetics
Cytogenetics
Cancer and Genome Integrity
Congenital Disorders
Transplantation
SESSION 8: ENZYME NANOTECHNOLOGY
The nanomaterials have ideal features to balance the key factors that decide the performance of biocatalysts, including precise surface area, resistance to mass transfer and efficient loading of enzymes. The latest enzyme immobilization scenario and techniques are discussed in this study. Some techniques that are useful in combining proteins/enzymes with nanoparticles are used. The immobilization method is to improve the operating efficiency of an enzyme for industrial applications. Various matrices have been identified in the literature so far to improve the efficiency of the enzymes immobilized. With the advent of nanotechnology, nanomaterials constitute novel and fascinating matrices for enzyme immobilization due to their special physico-chemical properties.
Enzyme nanoparticles
DNA nanotechnology
Nanotechnology products
DNA microarray
Nanopolymers
Nanotechnology in targeted drug delivery
Immobilization using nanoparticles
Nanotechnology enabled enzyme activity
SESSION 9: BIOCHEMISTRY, BIOPHYSICS AND STRUCTURAL BIOLOGY
To their functional behavior in the cell, chemical, physical and structural aspects of each molecule relate. These chemical interactions, binding behavior, binding energy, and other physical factors that contribute to a biomolecule's biophysics. In terms of their binding and structural integrity, structural biology deals with strategic interaction of each molecule with another. The chemical reactions associated with each of them serve as the basis of the molecule's biochemistry. In specific, protein biochemistry, which is involved in human body metabolism today,.
SESSION 10: ENZYMES IN FOOD TECHNOLOGY
In food technology, enzymes are equally important as they are in other fields. Most generally, food storage and fermentation enzymes are used. In different phases of production, cheese and brewing depend on enzyme activity. Traditional food products rely on enzymes, such as yoghurt and many more. The bread most frequently used is also an end result of the enzymatic reaction. Enzymes used may be endogenous, such as amylase used in mashing, such as wise yogurt. Enzyme accessibility of substrate.
SESSION 11: BIO IMAGING, BIOMECHANICS AND BIO MOLECULAR ENGINEERING
The ability of biomedical engineers to better understand the nature of the human body and the roles of living organisms has been dramatically improved by recent developments in computational and bioimaging techniques. In particular, recent advanced methods of computing, mathematics, and physics have helped researchers develop advanced techniques that can solve problems in the fields of bionics and biomechanics and improve the visualization of biological systems and the design of new medical devices. Prominent examples include tagged magnetic resonance imaging to study biomechanics of the brain and medical ultrasound imaging to mimic echolocation of animals. Such advances in imaging and visualization methods in bionics and biomechanical science help to define, classify and measure trends.
The application of engineering concepts and methods to the purposeful manipulation of molecules of biological origin is bio-molecular engineering. In enzymes, antibodies, DNA hybridization, bio-conjugation/bio-immobilization and bio-separations, the thermodynamics and kinetics of molecular recognition are studied.
SESSION 12: TRUCTURAL BIOCHEMISTRY, SYNTHETIC ENZYMES AND CROSS LINKING
Enzyme/Structural Biochemistry. Enzymes are macromolecules which help biological systems to accelerate (catalyze) chemical reactions. Typically, this is achieved by accelerating reactions by reducing the state of transition or decreasing the energy of activation. The catalytic groups are referred to as these residues. It has been shown that enzymes made from artificial molecules that do not occur anywhere in nature cause chemical reactions in the laboratory, challenging existing views on the conditions required to allow life to occur. The world's first enzymes made from artificial genetic material have been developed by a research team.
In the laboratory, synthetic enzymes made from molecules that do not occur anywhere in nature can cause chemical reactions. As complex scaffolds and as mechanisms for controlled release, enzyme systems such as tyrosinases, transferases and lysyl oxidases exhibit interesting features. Hydrogels produced by crosslinking of precursors by transferases or peroxidases as catalysts are currently receiving increased attention. Enzyme-mediated crosslinking has proved its efficiency and focus has now moved to the production of higher degrees of complexity of enzymatically crosslinked hydrogels, mimicking extracellular matrices. Moreover, for the development of complex nano-scale architectures, bottom-up approaches incorporating biocatalysts and self-assembly are being explored. The use of enzymatic crosslinking for the preparation of hydrogels will be explored in this analysis as a ground-breaking alternative to other methods of crosslinking, such as widely used UV-mediated photo-crosslinking or physical crosslinking.
SESSION 13: CELL SIGNALLING
Cell signalling is part of any mechanism of communication that regulates basic cell activities and coordinates all cell behavior. The ability of cells to perceive their microenvironment and react correctly is the basis of growth, tissue repair, and immunity, as well as normal homeostasis of tissues. Errors in signaling interactions and processing of cellular information are responsible for diseases such as autoimmunity from cancer and diabetes. Cells have proteins called receptors that bind and activate a physiological response to the signalling molecule. Via protein action, ion channel opening or enzyme activation, receptors turn external signals into internal ones.
Signal transduction mechanism
Receptor activity
Signal pathways
Kinase targets
G-protein
SESSION 14: INTRODUCTION TO CRISPR/Cas9 SYSTEM AND GENOME EDITING
Although recent programmable editing methods, such as zinc finger nucleases and transcription activator-like effector nucleases, have greatly enhanced the ability to precisely alter the genome, there are limitations to these techniques. CRISPR (clustered frequently interspaced short palindromic repeats)/Cas9 technology represents a major enhancement, achieving a new level of targeting, performance, and ease of use over these other next-generation genome editing methods. In virtually any organism, the CRISPR/Cas9 method allows for site-specific genomic targeting.
Editing the genome is a way of making specific changes to a cell or organism's DNA. An enzyme cut is the DNA in a particular series, and a modification or 'edit' is made to the sequence when this is repaired by the cell.
SESSION 15: NATURE AND FUNCTIONS OF CELL
A cell is enclosed by a plasma membrane that forms a selective barrier which allows the entry of nutrients and the exit of waste products. Many specialized compartments, or organelles, each enclosed by a separate membrane, organize the interior of the cell. The genetic material essential for cell growth and reproduction is found in one main organelle, the nucleus. Each cell contains only one nucleus, while in the cellular material or cytoplasm, other forms of organelles are present in several copies. Organelles include mitochondria, which are responsible for the energy transactions required for the survival of the cell; lysosomes, which digest unwanted materials inside the cell; and the endoplasmic reticulum and the Golgi apparatus, which play an important role in the cell's internal organization by synthesizing and refining, sorting and directing selected molecules to their proper place. In addition, plant cells produce photosynthesis-responsible chloroplasts, whereby the energy of sunlight is used to turn carbon dioxide (CO2) and water (H2O) molecules into carbohydrates. The gap in the cytoplasm called the cytosol is between all these organelles. The cytosol comprises an ordered fibrous molecular structure that forms the cytoskeleton, which gives its form to a cell, allows organelles to move inside the cell, and provides a mechanism by which the cell can move itself. More than 10,000 different types of molecules that are involved in cellular biosynthesis, the process of producing large biological molecules from small ones, are also present in the cytosol.
SESSION 16: CELL IMMUNOLOGY
The cell is the fundamental unit of all known living organisms, structural, biological and functional, and it is the smallest unit of life. The study of the building blocks of life includes cells. The human body is made up of trillions of cells that provide the framework for the body to turn nutrients from food into energy and perform specialized functions. Via fungus, poisoning, overheating or lack of oxygen, the cells die. In the medical and biological sciences, immunology is essential and it also protects us from infection across different lines of defense. The immune system does not work as it should, which can lead to diseases such as autoimmunity, cancer cells, and allergies. Sections of the immune system organs, including the thymus, spleen, bone marrow, lymph nodes, and other lymphatic tissues, may be surgically excised for consideration when patients are still alive when health problems escalate to emergency level. Immunological memory refers to the immune system's ability to respond more compactly to exposure to the same antigen in succession.
SESSION 17: CELL PHYSIOLOGY AND BIOCHEMISTRY
The biological research concerning the processes that take place in a cell to keep it alive is cell physiology. This includes cells from animals, microorganisms, and cells from plants. The word physiology applies to all the normal roles that exist in a living organism. Organ-systems are a collection of cells, tissues, and organs that have dedicated body functions. The role of Cell Physiology is organ-systems. Biochemistry is the study of chemical processes related to living organisms. Biochemical metabolism, proteins, and molecular genetics were split into three areas. Biochemistry focuses on understanding how biological molecules give rise to processes that occur within cells and cells that, in turn, are closely linked to the understanding and study of tissues, species, organ structure, and function. Pets, cells, plants, viruses, and microorganisms are the foundations of cell physiology.
SESSION 18: CELL CYCLE AND CYTOGENETICS
The cell differentiation or cell cycle is the sequence of events that occur in a cell to produce two daughter cells, leading to its multiplication and division of its DNA (DNA replication). It plays an important role in embryo formation, and also in the production and growth of our bodies. Mitosis creates new cells and replaces old, damaged or lost cells, and a cell divides to form two identical daughter cells in mitosis. Cytogenetics is a branch of gene technology that is concerned with how chromosomes, particularly their actions during meiosis and mitosis, contribute to cell behavior. The first labeling technique used to create precise banding was Quinacrine banding patterns. This process requires a fluorescence microscope and is no longer as commonly used as the banding of Giemsa. The causes of cell sorting are cancer by accelerating rates of cell division or preventing normal system controls, such as programmed cell death or arrest of the cell cycle.
SESSION 19: CANCER GENOMICS
Cancer genomics is the study of the entirety of gene expression and DNA Sequence differences between normal host cell and tumor cells. It is the promise of precision cancer treatment a focus on the independent tumor in the individual patient. Cancers types are including breast cancer, ovarian, colorectal, and prostate cancer as well as some other, less common, rarely certain types of cancer can be passed down through generations and environment. The symptoms of cancer may become depressed and anxious post diagnosis the risk of suicide in people with cancer is roughly double.
SESSION 20: ANIMAL CELLS AND MICROBIAL INTERACTIONS
Animal cells are representative of the eukaryotic cell, enclosed by a plasma membrane and containing a membrane-bound nucleus and organelles and different from the eukaryotic cells of plants and fungi, animal cells do not have a cell wall. Microbial genetics Interaction between various microorganisms and include both positive and negative interaction, also it is an assemblage of species living close enough for potential interactions and within a community different consortia may be found. The various types of microbes in an interaction are identified and characterized by several methods. Interaction may change over time, Bioleaching and wastewater treatment plants are non-sterile environments. Therefore, various types of microorganisms will live common in a community, the interactions between the microbes matter much for the outcome of the processes.
SESSION 21: HUMAN GENOMICS
Human genomics is the study of the provision as it occurs in human beings. The Human genome is the total set of nucleic acid sequences for humans, encoded as DNA within the 23 chromosome couple in cell nuclei and in a small DNA molecule found within own mitochondria. Human genomes involve both protein-coding DNA genes and noncoding DNA. Human genetics encompasses a differently of overlapping fields including classical genetics , cytogenetic, molecular genetics, biochemical genetics, genomics, developmental genetics, genetic counselling and clinical Ethic genetics. Human genetic variation is the genetic differences in whole populations, there may be multiple variants of any given gene in the human population, a situation called polymorphism. No two humans are genetically identical, even monozygotic twins having infrequent genetic differences due to mutations occurring during improvement and gene copy-number variation.
SESSION 22: DATA INTEGRATION, MODELLING AND PREDICTION
Data integration is the procedure of combining data generated using a variety of different research various in order to enable detection of underlying themes and in Computational biology and bioinformatics, biological principles. Data Analysis in this arena is data intensive, which means data sets are large and highly heterogeneous, to create knowledge from data, researchers must integrate these large and diverse datasets. Predictive genomics is at the intersection of multiple disciplines as predictive medicine, translational bioinformatics and personal genomics. Specifically, predictive genomics deals with the future phenotypic outcomes through prediction in areas such as complex multifactorial diseases in humans. Prediction and Modelling involves the use of computer simulations of biological systems, including cellular subsystems, such as the networks of enzymes and metabolites which comprise metabolism, signal transduction pathways and gene technology regulatory networks, to both visualize and analyze the complex connections of these cellular processes.
